Portfolio
What We’ve Built
Sovereign IT infrastructure for a drug-repurposing start-up
Working directly alongside the founders, we designed and built the complete IT infrastructure for a life sciences start-up from the ground up — with sovereignty as a guiding principle from day one. Every system is under the client’s full control, documented, and built to last beyond any single vendor relationship.
Services & infrastructure
We deployed GitLab as the company’s central development platform, including a container registry and Python package repository, running as infrastructure-as-code on Linux servers across multiple locations connected via a Tailscale VPN. Alongside this we built a custom Django web application for tracking datasets and analysis runs, a company dashboard linking all services and documentation, monitoring via Uptime Kuma with alerting through ntfy.sh, and a secure data exchange portal (ProjectSend) for sharing results with external partners.
Cybersecurity & compliance
Acting as cybersecurity lead, we implemented a VPN-first network architecture (Tailscale), a mobile device management policy including mandatory 2FA, and a structured backup strategy based on the 3-2-1 principle, extended with ZFS snapshots and long-term vault backups on a Synology NAS with off-site replication. Together with the founders we authored the company’s Quality Manual covering IT governance and data security, loosely based on ISO 27001.
Data science & NGS workflows
We built and maintain reproducible data processing pipelines for Next Generation Sequencing data (RNA-Seq, 3’ RNA-Seq and scRNA-Seq) using Snakemake and custom Python packages. These pipelines run across the company’s own servers, rented bare-metal servers (Hetzner), and SURF’s Snellius supercomputer — the latter arranged through SMB compute grants. We also developed data science tooling for querying NCBI GEO and ENA APIs, and contributed to the development of Transcriptome-based Activation Profiling (TAP) models for quantifying signal transduction pathway activation.
Oncology Analytics — Philips Research
Contributed to the rollout of an oncology analytics product for Philips IntelliSpace Precision Medicine, building ETL workflows in Apache Airflow backed by PostgreSQL. A key part of this work was translating the software across environments: from Linux VMs to containers to HPC batch processing clusters.
20+ years of personal sovereign infrastructure
We practice what we preach. For over two decades, Linux servers have been a home environment — running Nextcloud for collaborative document management, Immich for photo management, Home Assistant for home automation, and Paperless-NGX for a paperless office, all self-hosted with Docker Compose and secured with ZFS-backed storage. This is where many of the patterns we bring to clients were first developed and proven.
What We’ve Guided
High Performance Computing & Bioinformatics — Erasmus MC, Rotterdam
Engaged as project lead at Erasmus Medical Center for two completed implementation plans: one for a High Performance Computing facility and one for a Bioinformatics support facility. Both plans delivered a governance model, financial underpinning, and a detailed technical design. The stakeholder landscape was deliberately complex — spanning the Board of Directors, department heads, Research IT teams, SURF, and scientists — and required structured working sessions (using Miro) to align diverse interests into a shared roadmap.
Software Development Lead — Philips Research
Over ten years leading software development projects and initiatives at Philips Research, working across academic and industrial research contexts. This included change management through documentation and internal training — moving teams toward a more modern software development culture — as well as contributing to the company’s intellectual property portfolio through patent authorship.
IT Architecture & Policy — DCDC Tx
Beyond building the infrastructure, we served as the founding IT architect for this life sciences start-up: advising on technology choices, shaping the governance framework, and co-authoring IT and data security policy. This included a Quality Manual modelled loosely on ISO 27001 — written to meet the requirements of a regulated life sciences environment without over-engineering a small, fast-moving organisation.
More projects will be added as we grow. Get in touch if you’d like to discuss how we can help your organisation.